School of Natural Sciences
Centre for Life Sciences

Profile of Faculty

Dr. Praveen Kumar Sharma, Ph.D

Assistant Professor
Centre for Life Sciences


E-Mail pksharma@cuj.ac.in

Ph.D. (2005) Banaras Hindu University, Varanasi, INDIA
NET-JRF (June 1999) Life Sciences
M.Sc. (1997-1999) Banaras Hindu University, Varanasi, INDIA

Area of Specialization  

Molecular Biology, Cell signalling, Neurobiology

Employment Record  
  1. Assistant Professor, Centre for Life Sciences, Central University of Jharkhand, India (May 2011 onwards)

  2. Assistant Professor on contract, Centre for Life Sciences, Central University of Jharkhand, India (July 2010 to May 2011)

  3. Post Doctoral Research Fellow (2007-2010) James Graham Brown Cancer Centre, University of Louisville, Louisville, KY, USA

Professional Membership  
  1. Indian Academy of Neurosciences

  2. Association of Gerontology (INDIA)

 

Publications  
  1. Ranjan S. Sharma P.K. Association of Brain Derived Neurotrophic factor (BDNF) gene SNP G196A with type 2 Diabetes and obesity: A Meta-Analysis. Research Journal of Pharmacy and Technology. (in Press)
  2. Ranjan S, Sharma PK (2016). Effect of Environmental Chemical Exposures on Epigenetics of Diseases: A Systematic Review. Int. J. of Life-Sciences Scientific Res. 2(4). 385–403.
  3. Gupta P, Sharma PK, Mir H, Singh R, Singh N, Kloecker GH, Lillard JW Jr, Singh S.(2014). CCR9/CCL25 expression in non-small cell lung cancer correlates with aggressive disease and mediates key steps of metastasis. Oncotarget 5( 20) 10170-10179.
  4. Rajesh Singh, Pranav Gupta,Praveen Kumar Sharma,Edwin W. Ades, Susan K. Hollingshead, Shailesh Singh, James W. Lillard Jr. (2014). Prediction and Characterization of helper T cell epitopes from pneumococcal surface adhesin A (PsaA). Immunology 141(4). 514-530.
  5. Christelle P El-Haibi, Praveen Sharma, Rajesh Singh, Pranav Gupta, Dennis D Taub, Shailesh Singh, James W Lillard (2013) Differential G protein subunit expression by prostate cancer cells and their interaction with CXCR5. Molecular Cancer. 12(1):64. DOI:10.1186/1476-4598-12-64
  6. El-Haibi CP, Singh R, Gupta P, Sharma PK, Greenleaf KN, Singh S, Lillard JW Jr. (2012) Antibody microarray analysis of signaling networks regulated by Cxcl13 and Cxcr5 in prostate cancer. J. Proteomics Bioinform.5(8):177-184.
  7. El-Haibi CP, Singh R, Sharma PK, Singh S, Lillard JW Jr. (2011) CXCL13 mediates prostate cancer cell proliferation through JNK signaling and invasion through ERK activation. Cell Prolif. 44(4):311-319
  8. Christelle P El Haibi, Praveen K Sharma, Rajesh Singh, Paul R Johnson, Jill Suttles, Shailesh Singh and James W Lillard Jr. (2010) PI3Kp110-, Src-, FAK- dependent and DOCK2-independent migration and invasion of CXCL13-stimulated prostate cancer Cells. Molecular Cancer, 9:85
  9. Rajesh Singh, Shailesh Singh, Praveen K Sharma, Udai P Singh, David E. Briles, Susan K. Hollingshead, James W. Lillard, Jr (2010) Helper T Cell Epitope- mapping reveals MHC-Peptide binding affinities that correlate with T helper cell responses to Pneumococcal Surface Protein A. PLos One 5:e9432
  10. Sharma PK, Singh R, Eaton J, Novakovic KR, Chun LWK, Grizzle WE, Singh S (2010). CCR9-CCL25 interaction inhibits drug induced apoptosis of prostate cancer cell. Int. J. Cancer. 127 (9); 2020-2030
  11. Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LWK, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW Jr (2009). Serum CXCL13 positively correlated with prostatic disease, prostate specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Lett. 283:29-35
  12. Thakur MK, Sharma PK (2008) Binding of Estrogen receptor alpha promoter to nuclear proteins of mouse cerebral cortex; effect of age, sex and gonadal steroids. Biogerontol 9:467-478
  13. Thakur MK, Sharma PK (2007) Transcription of estrogen receptor α and β in mouse cerebral cortex: effect of age, sex, 17 β estradiol and testosterone. Neurochem Int 50:314-321
  14. Sharma PK, Thakur MK (2006) Expression of estrogen receptor (ER) α and β in mouse cerebral cortex: effect of age, sex, and gonadal steroids. Neurobiol. Aging 27:880-887
  15. Gaur P, Thakur BK, Sharma PK, Oka T, Thakur MK (2005). Expression of perchloric acid soluble 14 kDa protein in mouse brain. Anal. Neurosci. 12: 12-15
  16. Sharma PK, Thakur MK (2004). Estrogen receptor α expression in mice kidney shows sex differences during aging. Biogerontol 5:375-381.
  17. Thakur MK, Sharma PK, Ghosh S, Mani ST (2004). Estrogen intervention in aging and longevity: problems and perspectives. Geriat. Gerontol Int 6: S259-S261.
  18. Thakur MK, Sharma PK (2006). Aging of Brain: Role of Estrogen. Neurochem. Res. 31:1389-1398.
Book Chapter  
  1. Thakur MK, Sharma PK, Ghosh S. (2005) Oestrogen effects in the brain: Implications for aging and Alzheimer’s disease. In Molecular and Cellular Neurobiology (eds. MK Thakur and S Prasad), Narosa Publishing House Pvt. Ltd., New Delhi. Pp 55-69.
No. of Presentations, Invited Talks at national and International Level   Nearly 40
Doctoral Student  
  1. Mr. Shovit Ranjan
M.Sc. Student  
  1. Ms. Anupma Mondal (DBT-BUILDER)
  2. Mr. Chavali Subrahmanyam
  3. Mr. Samir Kumar Beura (DBT-BUILDER)
Research Support:   Group leader, DBT BUILDER Project (BT/PR9028/INF/22/193/2013) to Centre for Life Sciences, Central University of Jharkhand (2014 to 2019)