School of Natural Sciences
Centre for Life Sciences

Profile of Faculty

Dr. Biswa Ranjan Meher

Ph.D., Department of Biotechnology, IIT Guwahati, India (2004-2009)
Master of Science, Department of Botany, Utkal University, India (2001-2003)
Bachelor of Science, Botany (Hons), Zoology, Chemistry, Sambalpur University

Assistant Professor, DBT-BUILDER
Centre for Life Sciences

Cell:
E-Mail brmeher@gmail.com

Research Interest  
  1. Molecular modelling and structure based drug/vaccine design for HIV infections and mosquito-borne diseases.
Post-Doctoral Research Experience  
  1. University of Kansas, Lawrence, Kansas, USA (2009-2010)
  2. Albany State University, Albany, Georgia, USA (2010-2013)
  3. University of Richmond, Richmond, Virginia,USA (2013-2014)
  4. Indian Institute of Science, Bangalore, India (2014-2016)
Professional Awards and Fellowship received  
  1. Awarded National Doctoral Fellowship (NDF) from AICTE, Govt. of India to pursue the PhD program at IIT Guwahati in 2006.
  2. Awarded DS Kothari Post-Doctoral Fellowship (DSKPDF) by UGC, Govt. of India for research and development in May 2014.
  3. Qualified for National Eligibility Test (NET)conducted by CSIR/ UGC.
  4. Qualified for GATE-2004 (Graduate Aptitude Test in Engineering) in Life Sciences.
Publications  
  1. Seema Patel* and B.R. Meher. (2016) A review on emerging frontiers of house dust mite and cockroach allergy research. Allergologia et Immunopathologia. (In Press)
  2. B.R. Meher*, A. Dixit, G. Bousfield, G.H. Lushington* (2015). Glycosylation effects on FSHFSHR interaction dynamics: A case study of different FSH glycoforms by Molecular Dynamics simulations. Plos One. 10(9): e0137897
  3. B.R. Meher, and Yixuan Wang* (2015). Exploring the drug resistance of V32I and M46L mutant HIV-1 protease to inhibitor TMC114: Flap Dynamics and binding free energy studies. Journal of Molecular Graphics and Modeling, 56, 60 -73.
  4. B.R. Meher*, M. V. Satish Kumar, and PradiptaBandhyopadhyay (2014). Interchain hydrophobic clustering promotes rigidity in HIV-1 Protease flap dynamics: New insights from Molecular Dynamics. Journal of Biomolecular Structure and Dynamics, 32, 899-915.
  5. Zhen-feng Xu, B.R. Meher, Darnashley Eustache and Yixuan Wang* (2014). Insight into the interaction of DNA bases and defective graphenes: Covalent or Non-covalent. Journal of Molecular Graphics and Modeling, 47, 8-17
  6. B.R. Meher, and Yixuan Wang* (2012). Binding of Single walled carbon nanotube to WT and mutant HIV-1 proteases: Analysis of flap dynamics and binding mechanism. Journal of Molecular Graphics and Modeling, 38,430-445.
  7. B.R. Meher*, M. V. Satish Kumar, Smriti Sharma and PradiptaBandhyopadhyay (2012). Conformational dynamics of HIV-1 Protease: A comparative molecular dynamics simulation study with multiple AMBER force fields. Journal of Bioinformatics and Computational Biology, 10 (06): 1250018.
  8. B.R. Meher, and Yixuan Wang* (2012). Interaction of I50V mutant and I50L/A71V double mutant to HIV-1 protease inhibitor TMC114 (Darunavir): Molecular Dynamics and Free energy studies. Journal of Physical Chemistry B, 116:1884-1900.
  9. B. R. Meher, M. V. Satish Kumar and PradiptaBandhyopadhyay* (2009). Molecular Dynamics simulation of HIV-protease with polarizable and non-polarizable force fields. Indian Journal of Physics, 83, 81-90 (Special issue in simulation).
  10. PradiptaBandhyopadhyay* and B. R. Meher, (2006). Drug resistance of HIV-1 protease against JE2147: I47V mutation investigation by molecular dynamics simulation. Chemical Biology and Drug Design, 67:155-161.
Book Chapters
 
  1. B.R. Meher*, and Seema Patel (2013). Structural and dynamical aspects of HIV-1 protease and its role in drug resistance. Advances in Protein Chemistry and Structural Biology, Vol 92, Dynamics of Protein and Nucleic Acids, Tatyana Karabencheva-Christova (Editor) Academic Press, 2013, pp. 299-324. ISBN: 978-0-12-411636-8.
Contributed papers in conference proceedings  
  1. B. R. Meher*, M. V. Satish Kumar and Kausik Sen (2008). Pressure induced conformational dynamics of HIV-1 protease: A Molecular Dynamics Simulation study. IEEE Computer Society, pp.118-122 doi:10.1109/ICIT.2008.39.
  2. L.K. Acharya, B.R. Meher, A.K. Mukherjee* (2004) Application of ISSR markers among crop species. In Proc. 8th Orissa Bigyan Congress. Bhubaneswar Chapter. Regional Plant Resource Centre, Bhubaneswar, Orissa, India, Dec 11-12th, 2004. pp. 60-65.